anti-CD18, 68-5A5, mouse monoclonal antibody
Product Sizes
100 ug
£432.00
691564-100UG
About this Product
- SKU:
- 691564
- Additional Names:
- Integrin beta-2, Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, Complement receptor C3 subunit beta, CD antigen CD18, ITGB2, CD18, MFI7
- Application:
- FACS, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 68-5A5
- Clonality:
- Monoclonal
- Concentration:
- 100 ug/ml
- Extra Details:
- It recognizes a transmembrane glycoprotein of 95 kDa, identified as CD18 or integrin-2 (Workshop III). It complexes non-covalently with either L, M, or X integrin (CD11a, b, or c) to form the heterodimers. LFA-1, MAC-1, and p150,95, respectively. LFA-1 is the receptor for three members of the Ig supergene family of proteins, ICAM-1 (CD54, ICCAM-2 (CD102), and Mac-1 and p150,95 bind to ICAM-1, fibrinogen, and IC3b. ICAM-3 (CD50). CD18/CD11 heterodimeric molecules are involved with cell/cell and cell/extracellular adhesion in immune and inflammatory responses. This Mab blocks these cellular interactions. 68-5A5 was clustered at the IIIrd International Workshop on human leucocyte differentiation antigens. Positive control: human PBL and tonsil.
- Formulation:
- PBS with 0.02% sodium azide
- Host:
- Mouse
- Immunogen:
- Stimulated human leucocytes
- Isotype:
- IgG2a, kappa
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Progen
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:691564
