anti-CD11c, EBS-CD-011, mouse monoclonal antibody
Product Sizes
100 ug
£433.75
691561-100UG
About this Product
- SKU:
- 691561
- Additional Names:
- Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150,95, CD antigen CD11c, ITGAX, CD11C
- Application:
- FACS, Immunocytochemistry, Immunofluorescence, Immunohistochemistry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- EBS-CD-011
- Clonality:
- Monoclonal
- Concentration:
- 100 ug/ml
- Extra Details:
- Integrin alpha-X (CD11c, leukocyte surface antigen p150/95, CR4, Axb2) is a type 1 transmembrane protein that traditionally combines with beta-2 chain to form a leukocyte-specific integrin known as inactivated-C3b (iC3b) receptor 4 (CR4). Integrin alpha-X/beta-2 shares similar properties of the integrin alpha-M/beta-2 in mediating adherence of neutrophils and monocytes to stimulated endothelial cells and in phagocytosis of complement coated particles. Abnormal expression of integrin alpha-X is characteristic of hairy cell leukemia (HCL) and is dependent upon activation of proto-oncogenes Ras and JunD. Integrin alpha-X is present on dendritic cells, macrophages and NK-cells. Upon activation, DCs present in skin (Langerhans cells, lining of nose, lung, stomach, intestine and blood can migrate to lymphoid tissues and interact with T- and B-cells to initiate and shape the immune response. Positive control: human dendritic cells. Human lymph node and tonsil.
- Formulation:
- PBS with 0.02% sodium azide
- Host:
- Mouse
- Immunogen:
- Human macrophages
- Isotype:
- IgG1, kappa
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Progen
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:691561
