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Antibodies

anti-CD11a, 87-6F9, mouse monoclonal antibody

Product Sizes
100 ug
£432.00
691559-100UG
About this Product
SKU:
691559
Additional Names:
Integrin alpha-L, CD11 antigen-like family member A, Leukocyte adhesion glycoprotein LFA-1 alpha chain, LFA-1A, Leukocyte function-associated molecule 1 alpha chain, CD antigen CD11a, ITGAL, CD11A
Application:
FACS, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
CE/IVD:
RUO
translate.label.attr.clone:
87-6F9
Clonality:
Monoclonal
Concentration:
100 ug/ml
Extra Details:
87-6F9 reacts with CD11a, a transmembrane molecule with 1,145 amino acid residues and a MW of 180 kDa. CD11a is expressed on lymphocytes, granulocytes, monocytes and macrophages. Levels on memory T-cells tend to increase. CD11a plays a key role in mediating leucocyte adhesion to endothelium during inflammatory response through binding to ICAM 1 (CD54). Other ligands are ICAM-2 and ICAM-3. It is also involved in many other T-cell functions and immune phenomena. When paired with CD18, it forms the integrin alphaLbeta2 adhesion. 87-6F9 potently blocks LFA-1 dependent homotypic cell aggregation and was typed in the IVth International Leucocyte Typing Workshop. Positive control: human leucocytes.
Formulation:
PBS with 0.02% sodium azide
Host:
Mouse
Immunogen:
Stimulated human leucocytes
Isotype:
IgG2b, kappa
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Please refer to datasheet
Supplier:
Progen
Type:
Antibody: Monoclonal Antibody
  • Manufacturer's Data Sheet:691559