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Antibodies

Anti-Asc (Tyr-144), Phosphospecific Antibody

Product Sizes
100 ul
£433.00
AP5631-100UL
About this Product
SKU:
AP5631
Additional Names:
Caspase, PYCARD, AIM, ASC, CARD5, TMS1
Application:
ELISA, Immunocytochemistry, Western Blot
Buffer:
PBS
CE/IVD:
RUO
Clonality:
Polyclonal
Conjugate:
Tyr-144 - Phosphorylated
Extra Details:
Our Asc (Tyr-144) rabbit polyclonal phosphospecific primary antibody from PhosphoSolutions is produced in-house. It detects human, mouse, and rat Asc (Tyr-144) and is antigen affinity purified. It is great for use in WB, ICC., ECM
Format:
Antigen Affinity Purified
Formulation:
PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol
Gene Details:
Pycard
Host:
Rabbit
Immunogen:
Asc (Tyr-144) phospho-peptide (coupled to KLH) corresponding to amino acid residues surrounding Tyr-144 in mouse Asc. This peptide sequence is highly conserved in human and rat Asc.
Isotype:
IgG
Molecular Weight:
22
Physical State:
Liquid
Purification:
Affinity purified rabbit serum
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Specificity:
This antibody was cross-adsorbed to unphosphorylated Asc (Tyr-144) peptide before affinity purification using phospho-Asc (Tyr-144) peptide. The antibody detects phosphorylated Asc (Tyr-144) in the inflammasome. In J774 macrophage cells primed with LPS and treated with nigericin, the antibody colocalized with an inflammasome marker, caspase-1 inhibitor (FAM-YVAD-FMK). In addition, the antibody det
Storage Conditions:
-20[o]C 50% glycerol. Aliquot. Avoid freeze/thaw cycles.
Type:
Antibody: Polyclonal Antibody