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Antibodies

Anti-SHANK1a (C-terminus) Antibody

Product Sizes
100 ul
£552.00
24180-100UL
About this Product
SKU:
24180
Additional Names:
SH3 and multiple ankyrin repeat domains 1, GKAP/SAPAP interacting protein, Somatostatin receptor interacting protein, SSTR interacting protein, SSTRIP, SPANK1
Application:
Western Blot
Buffer:
PBS
CE/IVD:
RUO
Clonality:
Polyclonal
Extra Details:
Our SHANK1a rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human, mouse, and rat SHANK1a and is antigen affinity purified. It is great for use in WB., Phosphosolutions
Format:
Antigen Affinity Purified
Formulation:
PBS + 0.02% NaN3
Gene Details:
SHANK1
Host:
Rabbit
Immunogen:
Synthetic peptide corresponding to amino acids from the C-terminal region of human Shank1a protein
Isotype:
IgG
Physical State:
Liquid
Purification:
Prepared from pooled rabbit serum by affinity purification using a column to which the peptide immunogen was coupled.
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Specificity:
Reacts with the C-terminal region of human, mouse and rat Shank1a protein.
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Type:
Antibody: Polyclonal Antibody
Immunohistochemistry of retinal tissue showing specific staining of Shank at 1:800 dilution. Images are 2048 X 2048, 12 bit, collected with a 40X water objective, 10 stacks 0.55 um per stack.
Immunocytochemistry of hippocampal neurons DIV 14 grown under control, ASD1, and ASD2 conditions. The fluorescence intensity of Shank positive puncta was measured using antibodies specific for Shank1, Shank2, and Shank3. Exemplary images (upper panel) and quantification of average puncta signal intensity of 10 cells per condition (lower panel). Merged images show additional DAPI staining of the nucleus. Neurons grown under ASD1 conditions show a significant decrease of synaptic Shank proteins, while neurons
Immunohistochemistry of mouse retinal sections showing specific staining of SHANK1.
Immunohistochemistry showing synaptic distribution of Shank1/2 and somato-synaptic distribution of Shank3 in the mouse hippocampus, codistribution with VGLUT1, no codistribution with VGLUT2. 5x magnification of hippocampus. Immunofluorescence staining of coronal sections from wild-type mice probed with Shank1-3 (white; green in merge) and VGLUT1 (white; red in merge) antibodies; green arrow points toward the intragranular mossy fibers where there is a prominent synaptic stain of Shank3; scale bar =300 um. I
Immunohistochemistry showing colocalization of Shank puncta with VGLUT1 puncta in the intragranular mossy fibers and the stratum moleculare of the dentate gyrus. Confocal immunofluorescence stainings of coronal sections from wild-type mice probed with the Shank1 (white; green in merge) and VGLUT1 (white; red in merge) antibodies. The upper rows (large squares) show the enlarged region (3 = SM; 2 = SG; 1 = PL; scale bar = 100 um), the bottom rows (small rectangles) show further enlargements (indicated in up