Rabbit anti Human secretory component (free)
Product Sizes
1 ml
£439.00
NM-RAHU-SC-HD-1ML
About this Product
- SKU:
- NM-RAHU-SC-HD
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Extra Details:
- Nordic
- Format:
- Delipidated, heat inactivated, lyophilized, stable whole antiserum. No preservative added. Total protein and IgG concentrations in the antiserum are comparable to those of pooled normal rabbit serum.
- Formulation:
- Delipidated, heat inactivated, lyophilized, stable whole antiserum. No preservative added. Total protein and IgG concentrations in the antiserum are comparable to those of pooled normal rabbit serum.
- Host:
- Rabbit
- Shipping Conditions:
- Ambient
- Specificity:
- Precipitating polyclonal Rabbit antiSerum to free Human secretory component.
- Source:
- Secretory component is present in human secretions bound to secretory IgA (sIgA) and in free form. Secretory IgA (sIgA) functions as a dimer or polymer and accounts for almost all specific mucosal antibody activity. A molecule of sIgA is made up of two molecules of IgA, one J chain and one SC (MW 65,000). The dimer IgA is transported into secretions by its binding to the SC on the epithelial cells. Under normal conditions, sIgA contains both subclasses IgA1 and IgA2, since both are capable of binding SC. SC also has an affinity for polymeric IgM. Purified free human secretory component isolated from pooled milk is used for immunization. Freund's complete adjuvant is used in the first step of the immunization procedure.
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles., 2-8[o]C working dilution. Avoid freeze/thaw cycles.
- Supplier:
- Nordic-MUbio
- Type:
- Antibody: Secondary Antibodies
- Manufacturer's Data Sheet:RAHu_slash_SC(HD)
