Anti-PD-1 [5C4.B8 (Nivolumab)]
Product Sizes
0.2 mg
£ POA
MBS488994-0.2MG
About this Product
- SKU:
- MBS488994
- Additional Names:
- Programmed cell death protein 1; Programmed cell death protein 1; programmed cell death protein 1; programmed cell death 1; CD_antigen: CD279; CD279; programmed death-1; programmed death 1 ; PD1; PD 1; Programmed cell death protein 1; hPD-1; hPD1; hPD 1; BMS-936558; MDX-1106;ONO-4538
- Application:
- Block/Inhibit/Neutralise, FACS, Flow Cytometry, Immunohistochemistry, Surface Plasmon Resonance
- translate.label.attr.clone:
- [5C4.B8 (Nivolumab)]
- Concentration:
- 1 mg/ml
- Isotype:
- IgG1, kappa
- Physical State:
- PBS with 0.02% Proclin 300.
- Purity:
- Purified. Protein A affinity purified
- Reactivities:
- Human, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Specificity:
- Nivolumab binds to the extracellular portion of human PD-1 (2.6 nM - Scatchard analysis and SPR) - the antibody also binds to cynomolgus PD-1 with a similar affinity (3.9 nM - SPR). The antibody does not bind to other immunoglobulin superfamily proteins such as CD28, CTLA-4, ICOS and BTLA. The epitope of Nivolumab for both human and cynomolgus PD-1 includes the sequences SFVLNWYR-MSPSNQTDKLAAFPEDR
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- MyBioSource
- Type:
- Antibody
- Manufacturer's Data Sheet:MBS488994
