Anti-EGFR [Matuzumab], Mouse IgG1
Product Sizes
0.2 mg
£ POA
MBS488887-0.2MG
About this Product
- SKU:
- MBS488887
- Additional Names:
- epidermal growth factor receptor isoform a; Epidermal growth factor receptor; epidermal growth factor receptor; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1; Anti-EGFR [Matuzumab]; ErbB-1; ERBB1; HER1; EGF; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1; EMD72000; mAb425; 425; mAb 425
- Application:
- Block/Inhibit/Neutralise, ELISA, FACS, Flow Cytometry, Immunofluorescence, Western Blot
- translate.label.attr.clone:
- [Matuzumab]
- Concentration:
- 1 mg/ml
- Host:
- Mouse
- Isotype:
- IgG1, kappa
- Physical State:
- PBS with 0.02% Proclin 300.
- Purity:
- Protein A affinity purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds the extracellular domain III of the human EGFR and does not cross react with murine EGFR. It was also reported that residues S460/G461 in EGFR domain III are essential components of the epitope. This antibody binds at a site distinct from the EGF binding site, preventing conformational re-arrangement required for dimerization, a process essential for high-affinitiy ligand bindi
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- MyBioSource
- Type:
- Antibody
- Manufacturer's Data Sheet:MBS488887
