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Antibodies

VISTA/B7-H5/VSIR (Negative Regulator of Immune Response)

Product Sizes
0.1 mg
£ POA
MBS4381248-0.1MG
About this Product
SKU:
MBS4381248
Additional Names:
V-type immunoglobulin domain-containing suppressor of T-cell activation; V-type immunoglobulin domain-containing suppressor of T-cell activation; V-type immunoglobulin domain-containing suppressor of T-cell activation; V-set immunoregulatory receptor; Platelet receptor Gi24; B7H5; DD1alpha; GI24; PD-1H; PDCD1 homolog; Platelet receptor Gi24; PP2135; Stress-induced secreted protein 1 (SISP1); V domain Ig suppressor of T cell activation (VISTA); V Set Immuno-Regulatory Receptor
Application:
ELISA, IHC-Paraffin
translate.label.attr.clone:
[VISTA/3007]
Clonality:
Monoclonal
Host:
Mouse
Isotype:
IgG2b, kappa
Physical State:
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Purity:
Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
VISTA/GI24 is a transmembrane protein expressed in bone, on embryonic stem cells (ESCs), and on tumor cell surfaces. On ESC s, Gi24 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state. On tumor cells, Gi24 both promotes MT1-MMP expression and activity and serves as a substrate for MT1-MMP. This increases the po
Storage Conditions:
Please refer to datasheet
Supplier:
MyBioSource
Type:
Antibody: Monoclonal Antibody
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