TIGIT/VSTM3/VSIG9 (Immune Checkpoint for Cancer)
Product Sizes
0.1 mg
£ POA
MBS4380856-0.1MG
About this Product
- SKU:
- MBS4380856
- Additional Names:
- T-cell immunoreceptor with Ig and ITIM domains; T-cell immunoreceptor with Ig and ITIM domains; T-cell immunoreceptor with Ig and ITIM domains; T cell immunoreceptor with Ig and ITIM domains; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain-containing protein 3; T-cell immunoreceptor with Ig and ITIM domains; V-set and immunoglobulin domain containing 9 (VSIG9); V-set and transmembrane domain containing 3 (VSTM3); Washington University Cell Adhesion Molecule (WUCAM)
- Application:
- ELISA, IHC-Paraffin
- translate.label.attr.clone:
- [TIGIT/3106]
- Clonality:
- Monoclonal
- Host:
- Mouse
- Isotype:
- IgG2b, kappa
- Physical State:
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
- Purity:
- Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- TIGIT is a checkpoint inhibitor which binds with high affinity to the poliovirus receptor (PVR), causing increased IL10 secretion, decreased IL12B secretion. TIGIT binding to PVR also causes the suppression of T cell activation by promoting the generation of mature immuno-regulatory dendritic cells. It is expressed at low levels on natural killer (NK) cells, as well as peripheral memory and regula
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- MyBioSource
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:MBS4380856
