Mouse anti Fbxw7/Cdc4 [FBOX 3a9/1]: Horseradish peroxidase (HRP)
Product Sizes
0.05 mg
£ POA
MBS375347-0.05MG
About this Product
- SKU:
- MBS375347
- Additional Names:
- F-box/WD repeat-containing protein 7 isoform 4; F-box/WD repeat-containing protein 7; F-box/WD repeat-containing protein 7; F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila); F-box protein FBW7; F-box protein FBX30; F-box protein SEL-10; homolog of C elegans sel-10; F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase; Archipelago homolog; AGO; Archipelago homolog; archipelago, Drosophila, homolog of; CDC4; DKFZp686F23254; F-box and WD repeat domain containing 7; F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila); F-box and WD-40 domain-containing protein 7; F-box protein FBW7; F-box protein FBX30; F-box protein SEL-10; F-box/WD repeat-containing protein 7; FBW6; FBW7; FBX30; FBXO30; FBXW6; FBXW7; FLJ16457; hAgo; hCdc4; homolog of C elegans sel-10; SEL-10; SEL10
- Application:
- IHC-Paraffin, Immunoprecipitation, Western Blot
- translate.label.attr.clone:
- [FBOX 3a9/1]
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Host:
- Mouse
- Isotype:
- IgG1
- Physical State:
- Purified IgG conjugated to Horseradish Peroxidase, supplied in Phosphate buffered saline (PBS) containing 0.01% Thiomersal
- Purity:
- Purified on protein A from tissue culture supernatant.
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody recognises F-box/WD repeat-containing protein 7 (Fbxw7), which is also known as cdc4 and SEL-10. The FBW7/Cdc4 F-box protein was first recognized by its ability to bind cyclin E and the SCF (FBW7) is now known to target c-Myc, c-Jun and Notch for degradation in addition to its role in cyclin E proteolysis. FBW7 negatively regulates several key oncoproteins and is a tumour suppressor
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- MyBioSource
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:MBS375347
