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Proteins and Peptides

BWA-522 intermediate-1

Product Sizes
50 mg
£ POA
HY-W877989-50MG
5 mg
£ POA
HY-W877989-5MG
100 mg
£ POA
HY-W877989-100MG
10 mg
£ POA
HY-W877989-10MG
25 mg
£ POA
HY-W877989-25MG
About this Product
SKU:
HY-W877989
Application:
Antibody Microarray
CAS Number:
2241315-66-0
Extra Details:
BWA-522 intermediate-1 is an intermediate in the synthesis of PROTAC BWA-522 (HY-149433) and serves as a ligand molecule for cereblon E3 ubiquitin ligase. BWA-522 is an orally active small molecule protein-targeting chimera (PROTAC) that has significant degradation effects on AR-FL and AR-V7[1].
Molecular Weight:
369.37
Purity:
99.27
References:
[1]Arvinas Operations, et al. Indazole based compounds and associated methods of use. World Intellectual Property Organization, WO2021194879 A1 2021-09-30.
Research Area:
cancer
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
PROTAC
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