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Boc-PEG4-Val-Cit-PAB-OH

Product Sizes
100 mg
£ POA
HY-W800625-100MG
50 mg
£ POA
HY-W800625-50MG
25 mg
£ POA
HY-W800625-25MG
1 g
£ POA
HY-W800625-1G
250 mg
£ POA
HY-W800625-250MG
About this Product
SKU:
HY-W800625
CAS Number:
2055024-54-7
Extra Details:
Boc-PEG4-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker featuring a Boc-protected amine; a hydrophilic PEG spacer; and a Val-Cit-PAB dipeptide. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The Boc protecting group may be removed with acid to reveal a primary amine which may be used in coupling reactions to form amides. The Val-Cit-PAB is cleaved by cellular proteases for efficient release of payloads to the cell.
Molecular Weight:
726.86
Research Area:
Cancer
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
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