(S)-ML188
Product Sizes
100 mg
£ POA
HY-W614623-100MG
25 mg
£ POA
HY-W614623-25MG
50 mg
£ POA
HY-W614623-50MG
10 mg
£ POA
HY-W614623-10MG
About this Product
- SKU:
- HY-W614623
- CAS Number:
- 1417700-12-9
- Extra Details:
- (S)-ML188 is a SARS-CoV 3-chymotrypsin-like protease (3CLpro) inhibitor (IC50: 1.5 μM). (S)-ML188 has antiviral activity with an EC50 value of 12.9 μM against SARS-CoV. (S)-ML188 inhibits the activity of 3CLpro via non-covalent binding and can be used in the study of SARS-CoV[1].
- Molecular Weight:
- 433.54
- References:
- [1]Turlington M, et al. Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding. Bioorg Med Chem Lett. 2013 Nov 15;23(22):6172-7.
- Research Area:
- Infection
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
