(Rac)-Ketoconazole
Product Sizes
Get quote
HY-W422288-1EACH
About this Product
- SKU:
- HY-W422288
- Additional Names:
- (Rac)-Ketoconazol; (Rac)-R 41400
- CAS Number:
- 79156-75-5
- Extra Details:
- (Rac)-Ketoconazole ((Rac)-R 41400) is an antifungal imidazole compound with oral activity. (Rac)-Ketoconazole interferes with ergosterol synthesis by inhibiting cytochrome P450-dependent 14α-sterol demethylase (CYP51); a key enzyme on the fungal cell membrane; leading to membrane dysfunction and ultimately inhibition of fungal growth and reproduction. (Rac)-Ketoconazole is indicated for studies of fungal infections[1].
- Molecular Weight:
- 531.43
- References:
- [1]Chenge J T, et al. Structural characterization and ligand/inhibitor identification provide functional insights into the Mycobacterium tuberculosis cytochrome P450 CYP126A1[J]. Journal of Biological Chemistry, 2017, 292(4): 1310-1329.
- Research Area:
- Infection
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
