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Molecular Biology

2'-O;4'-C-Methyleneguanosine

Product Sizes
250 mg
£ POA
HY-W406070-250MG
100 mg
£ POA
HY-W406070-100MG
About this Product
SKU:
HY-W406070
Additional Names:
LNA-G
Application:
Antibody Microarray
CAS Number:
207131-16-6
Extra Details:
2′-O;4′-C-Methyleneguanosine (LNA-G) is a reverse guanine analog; where LNA (locked nucleic acid) is a nucleic acid analog. LNA modification can be widely used in various fields; such as effective binding affinity with complementary sequences and stronger nuclease resistance than natural nucleotides; providing great potential for application in disease diagnosis and research. 2'-O;4'-C-Methyleneguanosine is a substrate for KOD DNA polymerase; which incorporates LNA-G nucleotides into growing DNA strands; including consecutive incorporations ; to generate full-length extension products[1].
Molecular Weight:
295.25
Purity:
99.22
References:
[1]Rakesh N Veedu, et al. Polymerase directed incorporation studies of LNA-G nucleoside 5′-triphosphate and primer extension involving all four LNAnucleotides. New J. Chem., 2010,34, 877-879
Research Area:
Others
Shipping Conditions:
Ambient
Storage Conditions:
4[o]C (Powder; protect from light)
Type:
Molecular Biology Reagents: Nucleic Acids
Pathway:
Cell Cycle/DNA Damage
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