2′-Deoxy-β-L-uridine
Product Sizes
250 mg
£ POA
HY-W353804-250MG
100 mg
£ POA
HY-W353804-100MG
500 mg
£ POA
HY-W353804-500MG
About this Product
- SKU:
- HY-W353804
- CAS Number:
- 31501-19-6
- Extra Details:
- 2'-Deoxy-β-L-uridine is a nucledside analogue and a specific substrate for the viral enzyme; shows no stereospecificity against herpes simplex 1 (HSV1) thymidine kinase (TK). 2′-Deoxy-β-L-uridine exerts antiviral activity via the interation of 5'-triphosphates with the viral DNA polymerase[1][2].
- Molecular Weight:
- 228.20
- Purity:
- 99.96
- References:
- [1]Spadari S, et al. L-thymidine is phosphorylated by herpes simplex virus type 1 thymidine kinase and inhibits viral growth. J Med Chem. 1992 Oct 30;35(22):4214-20. |[2]Lin TS, et al. Design and synthesis of 2',3'-dideoxy-2',3'-didehydro-beta-L-cytidine (beta-L-d4C) and 2',3'-dideoxy 2',3'-didehydro-beta-L-5-fluorocytidine (beta-L-Fd4C), two exceptionally potent inhibitors of human hepatitis B virus (HBV) and potent inhibitors of human immunodeficiency virus (HIV) in vitro. J Med Chem. 1996 Apr 26;39(9):1757-9.
- Research Area:
- Infection
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Molecular Biology Reagents: Nucleic Acids
- Pathway:
- Cell Cycle/DNA Damage
