(E)-Guanabenz
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HY-W263279-1EACH
About this Product
- SKU:
- HY-W263279
- Additional Names:
- (E)-Wy-8678
- CAS Number:
- 60329-03-5
- Extra Details:
- (E)-Guanabenz ((E)-Wy-8678) is an orally active central α2-adrenoceptor agonist. (E)-Guanabenz has antihypertensive activity; acts via stimulating central α2-adrenoceptors; and reducing net sympathetic outflow into the periphery. (E)-Guanabenz also directly binds to and inhibits GADD34; and has neuroprotective activity. (E)-Guanabenz can be used for researching hypertension and Parkinson disease[1][2].
- Molecular Weight:
- 231.08
- References:
- [1]Sun X, et al. Guanabenz promotes neuronal survival via enhancement of ATF4 and parkin expression in models of Parkinson disease. Exp Neurol. 2018 May;303:95-107.|[2]Xie J, et al. LC-MS/MS determination of guanabenz E/Z isomers and its application to in vitro and in vivo DMPK profiling studies. J Pharm Biomed Anal. 2021 Oct 25;205:114331.
- Research Area:
- Neurological Disease; Cardiovascular Disease
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
