Carboxymethyl chitosan
Product Sizes
5 g
£ POA
HY-W250111-5G
1 g
£ POA
HY-W250111-1G
About this Product
- SKU:
- HY-W250111
- CAS Number:
- 83512-85-0
- Extra Details:
- Carboxymethyl chitosan is a derivative of chitosan. Carboxymethyl chitosan inhibits Apoptosis and ROS. Carboxymethyl chitosan increases the expression of Bcl-2 and reduces the expression of Bax; cytochrome c and caspase-3. Carboxymethyl chitosan inhibits the migration of various cells. Carboxymethyl chitosan exerts antitumor effects on Lewis tumors and hepatocarcinoma[1][2][3][4][5][6][7][8].
- Molecular Weight:
- N/A
- Purity:
- 0
- References:
- [1]Chen XG, et al. The effect of carboxymethyl-chitosan on proliferation and collagen secretion of normal and keloid skin fibroblasts. Biomaterials. 2002 Dec;23(23):4609-14.|[2]Kruczkowska W, et al. Medical Applications and Cellular Mechanisms of Action of Carboxymethyl Chitosan Hydrogels. Molecules. 2024 Sep 13;29(18):4360.|[3]He B, et al. Carboxymethylated chitosan protects Schwann cells against hydrogen peroxide-induced apoptosis by inhibiting oxidative stress and mitochondria dependent pathway. Eur J Pharmacol. 2018 Apr 15;825:48-56.|[4]Jiang Z, et al. Carboxymethyl chitosan represses tumor angiogenesis in vitro and in vivo. Carbohydr Polym. 2015 Sep 20;129:1-8.|[5]Chen Q, et al. Carboxymethyl-chitosan protects rabbit chondrocytes from interleukin-1beta-induced apoptosis. Eur J Pharmacol. 2006 Jul 10;541(1-2):1-8.|[6]Jiang Z, et al. Evaluation on biological compatibility of carboxymethyl chitosan as biomaterials for antitumor drug delivery. J Biomater Appl. 2017 Feb;31(7):985-994.|[7]Jiang Z, et al. Preparation and anti-tumor metastasis of carboxymethyl chitosan. Carbohydr Polym. 2015 Jul 10;125:53-60.|[8]Yang Z, et al. Acute toxicity of high dosage carboxymethyl chitosan and its effect on the blood parameters in rats. J Mater Sci Mater Med. 2012 Feb;23(2):457-62.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; sealed storage; away from moisture)
- Type:
- Assay Kits
- Pathway:
- Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB;Others
