Azido-PEG4-Val-Cit-PAB-MMAE
Product Sizes
1 mg
£ POA
HY-W190943-1MG
10 mg
£ POA
HY-W190943-10MG
5 mg
£ POA
HY-W190943-5MG
About this Product
- SKU:
- HY-W190943
- CAS Number:
- 1869126-64-6
- Extra Details:
- Azido-PEG4-Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC by using the anti-mitotic agent; monomethyl auristatin E (MMAE; a tubulin inhibitor); linked via the cleavable linker Azido-PEG4-Val-Cit-PAB-OH[1]. Azido-PEG4-Val-Cit-PAB-MMAE is a click chemistry reagent; it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Molecular Weight:
- 1396.71
- Purity:
- 99.43
- References:
- [1]Moreadith R, et, al. Polyoxazoline antibody drug conjugates. WO2016019340A1.
- Research Area:
- Cancer
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C (Powder; protect from light; stored under nitrogen)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
- Pathway:
- Antibody-drug Conjugate/ADC Related
