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Proteins and Peptides

Cyclo(glycyl-L-leucyl)

Product Sizes
250 mg
£ POA
HY-W152604-250MG
10 mg
£ POA
HY-W152604-10MG
100 mg
£ POA
HY-W152604-100MG
50 mg
£ POA
HY-W152604-50MG
25 mg
£ POA
HY-W152604-25MG
5 mg
£ POA
HY-W152604-5MG
About this Product
SKU:
HY-W152604
Additional Names:
Cyclo(leu-gly)
CAS Number:
5845-67-0
Extra Details:
Cyclo(glycyl-L-leucyl) (Cyclo(leu-gly)); a neuropeptide; down-regulates dopamine (DA) receptors and attenuates dopaminergic supersensitivity. Cyclo(glycyl-L-leucyl) inhibits the development of Morphine induced pain relief as well as dopamine receptor supersensitivity in rats. Cyclo(glycyl-L-leucyl) has the potential for the prevention of tardive and/or L-DOPA (HY-N0304)-induced dyskinesias[1][2].
Molecular Weight:
170.21
Purity:
99.79
References:
[1]J Z Fields, et al. The effects of cyclo(leucyl-glycyl) on nigrostriatal dopaminergic supersensitivity--inhibition of apomorphine-induced climbing. Neuropeptides. 1990 Aug;16(4):207-11.|[2]H N Bhargava, et al. Cyclo (leucylglycine) inhibits the development of morphine induced analgesic tolerance and dopamine receptor supersensitivity in rats. Life Sci. 1980 Jul 14;27(2):117-23.
Research Area:
Neurological Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
-80[o]C; 2 years; -20[o]C; 1 year (Powder; sealed storage; away from moisture)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
Pathway:
GPCR/G Protein;Neuronal Signaling
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