1-Oleoyl-sn-glycero-3-phosphocholine
Product Sizes
5 mg
£ POA
HY-W140439-5MG
25 mg
£ POA
HY-W140439-25MG
100 mg
£ POA
HY-W140439-100MG
1 mg
£ POA
HY-W140439-1MG
50 mg
£ POA
HY-W140439-50MG
10 mg
£ POA
HY-W140439-10MG
10mM/1mL
£ POA
HY-W140439-10MM
About this Product
- SKU:
- HY-W140439
- Additional Names:
- 18:1 Lyso PC
- CAS Number:
- 19420-56-5
- Extra Details:
- 1-Oleoyl-sn-glycero-3-phosphocholine (18:1 Lyso PC); a lysophospholipid; is a GPR82 inhibitor. 1-Oleoyl-sn-glycero-3-phosphocholine abrogates constitutive Gi-coupled GPR82 activity; shifts active/inactive equilibrium to inactive; suppresses Gi protein activation; increases cAMP production; and decreases GTPγS binding to Gαi proteins. 1-Oleoyl-sn-glycero-3-phosphocholine contributes to adipocyte lipolysis regulation.1-Oleoyl-sn-glycero-3-phosphocholine exhibits reduced serum levels in mouse models of steatohepatitis; linked to hepatic Lpcat 1-4 up-regulation[1][2].
- Molecular Weight:
- 521.67
- Purity:
- 99.58
- References:
- [1]Soupene E, Fyrst H, Kuypers FA. Mammalian acyl-CoA:lysophosphatidylcholine acyltransferase enzymes. Proc Natl Acad Sci U S A. 2008;105(1):88-93.|[2]Florin-Christensen J, Narvaez-Vasquez J, Florin-Christensen M, Ryan CA. A method for distinguishing 1-acyl from 2-acyl lysophosphatidylcholines generated in biological systems. Anal Biochem. 1999;276(1):13-17.
- Research Area:
- Inflammation/Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C; 3 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Others
