1-Formyl-beta-carboline
Product Sizes
50 mg
£ POA
HY-W130965-50MG
25 mg
£ POA
HY-W130965-25MG
10 mg
£ POA
HY-W130965-10MG
5 mg
£ POA
HY-W130965-5MG
100 mg
£ POA
HY-W130965-100MG
10mM/1mL
£ POA
HY-W130965-10MM
About this Product
- SKU:
- HY-W130965
- CAS Number:
- 20127-63-3
- Extra Details:
- 1-Formyl-beta-carboline is an alkaloid with inhibitory activity against Newcastle disease virus (NDV). 1-Formyl-beta-carboline can effectively inhibit different genotypes of NDV with IC50 values within 10 μM; and its inhibition rate is more than 90% at a concentration of 20 μM. 1-Formyl-beta-carboline mainly exerts its effects by inhibiting the adsorption and entry processes in the NDV life cycle. 1-Formyl-beta-carboline has been identified as a novel HN inhibitor that can directly interact with the NDV HN protein and affect the adsorption of NDV. 1-Formyl-beta-carboline also inhibits the entry of NDV by inhibiting the PI3K/Akt signaling pathway rather than the ERK pathway[1].
- Molecular Weight:
- 196.21
- Purity:
- 99.70
- References:
- [1]1-Formyl- β-carboline Derivatives Block Newcastle Disease Virus Proliferation through Suppressing Viral Adsorption and Entry Processes
- Research Area:
- Infection
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Anti-infection;PI3K/Akt/mTOR
