CL 5343 (Standard)
Product Sizes
100 mg
£ POA
HY-W074975R-100MG
5 mg
£ POA
HY-W074975R-5MG
10 mg
£ POA
HY-W074975R-10MG
25 mg
£ POA
HY-W074975R-25MG
50 mg
£ POA
HY-W074975R-50MG
About this Product
- SKU:
- HY-W074975R
- Additional Names:
- 5-Amino-1;3;4-thiadiazole-2-sulfonamide (Standard)
- CAS Number:
- 14949-00-9
- Extra Details:
- CL 5343 (Standard) is the analytical standard of CL 5343. This product is intended for research and analytical applications. CL 5343 (5-Amino-1;3;4-thiadiazole-2-sulfonamide) is an inhibitor of human carbonic anhydrase B (HCA-B). CL 5343 can serve as a CA9 ligand to achieve the targeted delivery of maytansinoid to the cell membrane of SKRC52 renal cancer cells[1][2].
- Molecular Weight:
- 180.21
- References:
- [1]Pesando JM, et al. Proton magnetic resonance studies of carbonic anhydrase. III. Binding of sulfonamides. Biochemistry. 1975;14(4):689-693.|[2]Pérez-Herrero E, et al. The reversed intra-and extracellular pH in tumors as a unified strategy to chemotherapeutic delivery using targeted nanocarriers[J]. Acta Pharmaceutica Sinica B, 2021, 11(8): 2243-2264.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Metabolic Enzyme/Protease
