1-Hydroxyphenazine
Product Sizes
100 mg
£ POA
HY-W068682-100MG
50 mg
£ POA
HY-W068682-50MG
10 mg
£ POA
HY-W068682-10MG
25 mg
£ POA
HY-W068682-25MG
10mM/1mL
£ POA
HY-W068682-10MM
About this Product
- SKU:
- HY-W068682
- Additional Names:
- Hemipyocyanine; 1-Phenazinol; Hemi-pyocyanin
- Application:
- Electron Microscopy
- CAS Number:
- 528-71-2
- Extra Details:
- 1-Hydroxyphenazine (Hemipyocyanine; 1-Phenazinol; Hemi-pyocyanin) is an inhibitor for α-Amylase with an IC50 of 3.1 μg/mL[1]. 1-Hydroxyphenazine exhibits anticancer and anti-inflammatory activity against cells A549; 1321N1 and RAW264.7; antifungal and antibacterial activity against strains Candida albicans; Aspergillus fumigatus; Escherichia coli and Xanthomonas campestris[2][3][4][5].
- Molecular Weight:
- 196.20
- Purity:
- 99.80
- References:
- [1]Nguyen TH, et al., Novel α-Amylase Inhibitor Hemi-Pyocyanin Produced by Microbial Conversion of Chitinous Discards. Mar Drugs. 2022 Apr 23;20(5):283. |[2]McFarland AJ, et al., Inhibition of autophagy by 3-methyladenine protects 1321N1 astrocytoma cells against pyocyanin- and 1-hydroxyphenazine-induced toxicity. Arch Toxicol. 2012 Feb;86(2):275-84|[3]Xiao J, et al., Anti-Inflammatory Effects of an Extract from Pseudomonas aeruginosa and Its Purified Product 1-Hydroxyphenazine on RAW264.7 Cells. Curr Microbiol. 2021 Jul;78(7):2762-2773.|[4]Prabhu MS, et al., Purification and molecular and biological characterisation of the 1-hydroxyphenazine, produced by an environmental strain of Pseudomonas aeruginosa. World J Microbiol Biotechnol. 2014 Dec;30(12):3091-9.|[5]Kerr JR, et al., Pseudomonas aeruginosa pyocyanin and 1-hydroxyphenazine inhibit fungal growth. J Clin Pathol. 1999 May;52(5):385-7.
- Research Area:
- Cancer; Infection; Metabolic Disease; Inflammation/Immunology; Neurological Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Store at room temperature; keep dry and cool
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Anti-infection;Metabolic Enzyme/Protease
