2'-O-Methylguanosine
Product Sizes
250 mg
£ POA
HY-W013260-250MG
100 mg
£ POA
HY-W013260-100MG
500 mg
£ POA
HY-W013260-500MG
1 g
£ POA
HY-W013260-1G
About this Product
- SKU:
- HY-W013260
- Application:
- Electron Microscopy
- CAS Number:
- 2140-71-8
- Extra Details:
- 2'-O-Methylguanosine is a modified nucleoside produced in tRNAs by the action of tRNA guanosine-2’-O-methyltransferase. 2'-O-Methylguanosine results in apoptotic changes of cells[1][2].
- Molecular Weight:
- 297.27
- Purity:
- 99.81
- References:
- [1]B C Persson, et al. The spoU gene of Escherichia coli, the fourth gene of the spoT operon, is essential for tRNA (Gm18) 2'-O-methyltransferase activity. Nucleic Acids Res. 1997 Oct 15;25(20):4093-7.|[2]T Mori, et al. Isolation and identification of apoptosis inducing nucleosides from CD57(+)HLA-DRbright natural suppressor cell line. Biochem Biophys Res Commun. 1998 Oct 20;251(2):416-22.|[3]Petushkov I, et al., Effects of natural RNA modifications on the activity of SARS-CoV-2 RNA-dependent RNA polymerase. FEBS J. 2023 Jan;290(1):80-92.
- Research Area:
- Cancer; Infection
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; stored under nitrogen)
- Type:
- Molecular Biology Reagents: Nucleic Acids
- Pathway:
- Apoptosis;Cell Cycle/DNA Damage
