2'-O-Methylcytidine
Product Sizes
100 mg
£ POA
HY-W011834-100MG
500 mg
£ POA
HY-W011834-500MG
1 g
£ POA
HY-W011834-1G
About this Product
- SKU:
- HY-W011834
- CAS Number:
- 2140-72-9
- Extra Details:
- 2'-O-Methylcytidine is an orally active 2'-substituted nucleoside as a inhibitor of HCV replication with antiviral activity. 2'-O-Methylcytidine inhibits RNA-dependent RNA polymerase (NS5B)-catalyzed RNA synthesis in vitro; in a manner that is competitive with substrate nucleoside triphosphate[1][2][3].
- Molecular Weight:
- 257.25
- Purity:
- 99.99
- References:
- [1]Steven S Carroll, et al. Inhibition of hepatitis C virus RNA replication by 2'-modified nucleoside analogs. J Biol Chem. 2003 Apr 4;278(14):11979-84|[2]Hingerty B, et al. The crystal and molecular structure of 2'-O-methylcytidine[J]. Acta Crystallographica Section B: Structural Crystallography and Crystal Chemistry, 1977, 33(5): 1349-1356.|[3]Del Vecchio AM, et al. Small molecule and biologic inhibitors of hepatitis C virus: a symbiotic approach. Mini Rev Med Chem. 2006 Nov;6(11):1263-8.
- Research Area:
- Infection
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; protect from light)
- Type:
- Molecular Biology Reagents: Nucleic Acids
- Pathway:
- Anti-infection;Cell Cycle/DNA Damage
