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Molecular Biology

2'-Deoxyuridine 5'-monophosphate (disodium)

Product Sizes
250 mg
£ POA
HY-W011142-250MG
10mM/1mL
£ POA
HY-W011142-10MM
About this Product
SKU:
HY-W011142
Additional Names:
dUMP (disodium)
Application:
Electron Microscopy
CAS Number:
42155-08-8
Extra Details:
2'-Deoxyuridine 5'-monophosphate (dUMP) disodium is a deoxynucleotide that is reductively methylated to dTMP (2'-deoxythymidine 5'-monophosphate) by bisubstrate enzyme thymidylate synthase (TS). dTMP is a nucleotide required for DNA synthesis[1].
Molecular Weight:
352.15
Purity:
99.97
References:
[1]Zachary Newby, et al. The role of protein dynamics in thymidylate synthase catalysis: variants of conserved 2'-deoxyuridine 5'-monophosphate (dUMP)-binding Tyr-261. Biochemistry. 2006 Jun 20;45(24):7415-28.|[2]Skouloubris S, et al. Targeting of Helicobacter pylori thymidylate synthase ThyX by non-mitotoxic hydroxy-naphthoquinones. Open Biol. 2015 Jun;5(6):150015.
Research Area:
Infection; Metabolic Disease
Shipping Conditions:
Ambient
Storage Conditions:
4[o]C (Powder; sealed storage; away from moisture and light)
Type:
Molecular Biology Reagents: Nucleic Acids
Pathway:
Metabolic Enzyme/Protease
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