1-Monopalmitin (Standard)
Product Sizes
25 mg
£ POA
HY-W009141R-25MG
10 mg
£ POA
HY-W009141R-10MG
5 mg
£ POA
HY-W009141R-5MG
100 mg
£ POA
HY-W009141R-100MG
50 mg
£ POA
HY-W009141R-50MG
About this Product
- SKU:
- HY-W009141R
- Additional Names:
- Glyceryl palmitate (Standard)
- CAS Number:
- 542-44-9
- Extra Details:
- 1-Monopalmitin (Glyceryl palmitate) (Standard) is the analytical standard of 1-Monopalmitin (HY-W009141). This product is intended for research and analytical applications. 1-Monopalmitin (Glyceryl palmitate) is an activator of the PI3K/Akt pathway and an inhibitor of P-glycoprotein (P-gp). 1-Monopalmitin can induce G2/M arrest and caspase-dependent apoptosis in cancer cells; while inhibiting IAPs protein expression. 1-Monopalmitin can increase drug accumulation by inhibiting P-gp activity in intestinal Caco-2 cells. 1-Monopalmitin has the ability to induce protective autophagy and apoptosis of lung cancer cells (IC50=50-58 μg/mL); with low toxicity to normal cells[1][2].
- Molecular Weight:
- 330.51
- References:
- [1]Tomoko Konishi, et al. A bitter melon extract inhibits the P-glycoprotein activity in intestinal Caco-2 cells: monoglyceride as an active compound. Biofactors. 2004;22(1-4):71-4.|[2]Niu L, et al. 1-Monopalmitin promotes lung cancer cells apoptosis through PI3K/A kt pathway in vitro. Environmental Toxicology, 2023, 38(11): 2621-2631.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Membrane Transporter/Ion Channel
