D-5-Hydroxytryptophan
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HY-W007223-1EACH
About this Product
- SKU:
- HY-W007223
- Additional Names:
- D-5-HTP; 5-Hydroxy-D-tryptophan
- CAS Number:
- 4350-07-6
- Extra Details:
- D-5-Hydroxytryptophan (D-5-HTP) is the D-isomer of 5-HTP and can be isolated from DL-5-hydroxytryptophan by continuous separation. Compared with intraperitoneal administration of L-5-Hydroxytryptophan; which can induce dose-dependent backward walking behavior in mice; D-5-Hydroxytryptophan has no significant effect on mouse behavior and is a negative control. D-5-Hydroxytryptophan is also a 5-HT ligand; capable of binding to the 5-HT site with affinity in the micromolar range[1][2][3].
- Molecular Weight:
- 220.23
- References:
- [1]J Arendt, et al. Alternative pathways of 5-hydroxyindole metabolism. II. The role transamination in the metabolism of D-5-hydroxytryptophan in the rat. Biochem Pharmacol. 1967 Mar;16(3):419-22.|[2]Shimomura K, et al. Backward walking induced by L-5-hydroxytryptophan in mice. Jpn J Pharmacol. 1981 Feb;31(1):39-46.|[3]Acton G. Effects of D-5-hydroxytryptophan and D-DOPA on binding at serotonin and dopamine receptors. Res Commun Chem Pathol Pharmacol. 1988 Apr;60(1):129-32.
- Research Area:
- Neurological Disease
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
