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1-Cbz-azetidine-3-carboxylic acid

Product Sizes
10 g
£ POA
HY-W004868-10G
25 g
£ POA
HY-W004868-25G
100 g
£ POA
HY-W004868-100G
About this Product
SKU:
HY-W004868
Application:
Antibody Microarray
CAS Number:
97628-92-7
Extra Details:
1-Cbz-azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Cbz-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]
Molecular Weight:
235.24
Purity:
99.66
References:
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.|[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.
Research Area:
Cancer
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Pathway:
Antibody-drug Conjugate/ADC Related;PROTAC
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