Itepekimab
Product Sizes
10 mg
£ POA
HY-P99673-10MG
1 mg
£ POA
HY-P99673-1MG
5 mg
£ POA
HY-P99673-5MG
About this Product
- SKU:
- HY-P99673
- Additional Names:
- REGN-3500; SAR-440340
- CAS Number:
- 2226742-52-3
- Extra Details:
- Itepekimab (REGN-3500) is an IgG4 monoclonal antibody against IL-33. Itepekimab reduced airway inflammation and related tissue damage in preliminary clinical studies. Itepekimab has potential effects in asthma; chronic obstructive pulmonary disease (COPD); and atopic dermatitis (AD)[1][2][3][4].
- Molecular Weight:
- (144.64 kDa)
- Purity:
- 99.40
- References:
- [1]Wechsler ME, et al. Efficacy and Safety of Itepekimab in Patients with Moderate-to-Severe Asthma. N Engl J Med. 2021 Oct 28;385(18):1656-1668.|[2]Kosloski MP, et al. Pharmacokinetics and pharmacodynamics of itepekimab in healthy adults and patients with asthma: Phase I first-in-human and first-in-patient trials. Clin Transl Sci. 2022 Feb;15(2):384-395.|[3]Rabe KF, et al. Safety and efficacy of itepekimab in patients with moderate-to-severe COPD: a genetic association study and randomised, double-blind, phase 2a trial. Lancet Respir Med. 2021 Nov;9(11):1288-1298.
- Research Area:
- Inflammation/Immunology
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Store at -80[o]C for 2 years
- Type:
- Antibodies
- Pathway:
- Immunology/Inflammation;NF-κB
