Cantuzumab ravtansine
Product Sizes
1 mg
HY-P99493-1MG
5 mg
HY-P99493-5MG
About this Product
- SKU:
- HY-P99493
- Additional Names:
- IMGN242; huC242-DM4
- Application:
- Antibody Microarray
- CAS Number:
- 868747-45-9
- Extra Details:
- Cantuzumab ravtansine (IMGN242; huC242-DM4); an ADC; is a humanized monoclonal antibody; huC242; covalently linked via a disulfide bond to DM4 (HY-12454). Cantuzumab ravtansine has broad antitumor efficacy against a range of CanAg-positive human tumor xenografts[1][2].
- Molecular Weight:
- 150000 (average)
- Purity:
- 98.71
- References:
- [1]Robert J. Lutz, et al. HuC242-DM4, an antibody-maytansinoid conjugate with superior preclinical activity in human CanAg-positive tumor xenograft models in SCID mice. Cancer Res (2005) 65 (9_Supplement): 334-335.|[2]Olga Ab, et al. Activity of huC242-DM4, an antibody-cytotoxic agent conjugate, used in combination with anti-neoplastic agents against gastric cancer cells in culture. Mol Cancer Ther (2007) 6 (11_Supplement): A127.
- Research Area:
- Cancer
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -80[o]C; protect from light
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
- Pathway:
- Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton
