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Antibodies

Amubarvimab

Product Sizes
1 mg
£ POA
HY-P99435-1MG
10 mg
£ POA
HY-P99435-10MG
5 mg
£ POA
HY-P99435-5MG
About this Product
SKU:
HY-P99435
Additional Names:
BRII-196
CAS Number:
2509447-07-6
Extra Details:
Amubarvimab (BRII-196) is a human IgG1 mAb that bind to non-competing epitopes on the receptor binding domain (RBD) of spike protein; with a KD of 5.88 nM. Amubarvimab can effectively neutralize SARS-CoV-2 variants[1][2].
Molecular Weight:
(143.84 kDa)
Purity:
95.00
References:
[1]Ji Y, et, al. Preclinical characterization of amubarvimab and romlusevimab, a pair of non-competing neutralizing monoclonal antibody cocktail, against SARS-CoV-2. Front Immunol. 2022 Sep 14;13:980435. |[2]Hoy SM. Amubarvimab/Romlusevimab: First Approval. Drug. 2022 Aug;82(12):1327-1331.
Research Area:
Infection
Shipping Conditions:
Dry Ice
Storage Conditions:
Store at -80[o]C for 2 years
Type:
Antibodies
Pathway:
Anti-infection
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