Amlitelimab
Product Sizes
5 mg
£ POA
HY-P99434-5MG
10 mg
£ POA
HY-P99434-10MG
1 mg
£ POA
HY-P99434-1MG
50 mg
£ POA
HY-P99434-50MG
25 mg
£ POA
HY-P99434-25MG
About this Product
- SKU:
- HY-P99434
- Additional Names:
- KY1005; SAR445229
- CAS Number:
- 2378692-15-8
- Extra Details:
- Amlitelimab () is an anti-OX40 Ligand (OX40L) monoclonal antibody (mAb). Amlitelimab inhibits OX40-OX40L interaction; and can be used in the research of atopic dermatitis[1][2][3].
- Molecular Weight:
- (145.94 kDa)
- Purity:
- 99
- References:
- [1]Ana Maria Lé, et al. OX40-OX40L Inhibition for the Treatment of Atopic Dermatitis-Focus on Rocatinlimab and Amlitelimab. Pharmaceutics 2022, 14(12), 2753. |[2]Saghari M, et al. OX40L Inhibition Suppresses KLH-driven Immune Responses in Healthy Volunteers: A Randomized Controlled Trial Demonstrating Proof-of-Pharmacology for KY1005. Clin Pharmacol Ther. 2022 May;111(5):1121-1132. |[3]Tkachev V, et al. Combined OX40L and mTOR blockade controls effector T cell activation while preserving Treg reconstitution after transplant. Sci Transl Med. 2017 Sep 20;9(408):eaan3085.
- Research Area:
- Inflammation/Immunology
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Store at -80[o]C for 2 years
- Type:
- Antibodies
- Pathway:
- Others
