Andecaliximab
Product Sizes
10 mg
£ POA
HY-P99351-10MG
1 mg
£ POA
HY-P99351-1MG
5 mg
£ POA
HY-P99351-5MG
25 mg
£ POA
HY-P99351-25MG
About this Product
- SKU:
- HY-P99351
- Additional Names:
- Anti-MMP9 Reference Antibody (andecaliximab)
- CAS Number:
- 1518996-49-0
- Extra Details:
- Andecaliximab is a recombinant chimeric IgG4 monoclonal antibody (mAb) targets matrix metalloproteinase 9 (MMP9). Andecaliximab shows the antifibrotic efficacy in idiopathic pulmonary fibrosis mouse models. Andecaliximab can be used for the research of gastric adenocarcinoma and idiopathic pulmonary fibrosis (IPF)[1][2].
- Molecular Weight:
- (150 kDa)
- Purity:
- 99.0
- References:
- [1]Andrew E. Greenstein, et al. Effect of andecaliximab (anti-MMP9) on proteolysis of IL-7 in vitro, TCR diversity in mice, and serum IL-7 in gastric cancer patients in combination with chemotherapy. 2018 ASCO-SITC Clinical Immuno-Oncology Symposium.|[2]Espindola MS, et al. Differential Responses to Targeting Matrix Metalloproteinase 9 in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2021 Feb 15;203(4):458-470.
- Research Area:
- Cancer
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Store at -80[o]C for 2 years
- Type:
- Antibodies
- Pathway:
- Metabolic Enzyme/Protease
