Lulizumab
Product Sizes
10 mg
HY-P99302-10MG
5 mg
HY-P99302-5MG
1 mg
HY-P99302-1MG
About this Product
- SKU:
- HY-P99302
- Additional Names:
- Humanized Anti-CD28 Recombinant Antibody
- CAS Number:
- 2235419-62-0
- Extra Details:
- Lulizumab (Humanized Anti-CD28 Recombinant Antibody) is an anti-CD28 domain antibody antagonist. Lulizumab inhibits T-cell activation by selectively targeting the CD28 signal. In a sensitized non-human primate kidney transplantation model; when combined with Carfilzomib (HY-10455); Lulizumab can regulate immune cells and prolong the survival time of the graft[1][2].
- Molecular Weight:
- (12.01 kDa)
- Purity:
- 95.0
- References:
- [1]Fernandes JC. Therapeutic application of antibody fragments in autoimmune diseases: current state and prospects. Drug Discov Today. 2018 Dec;23(12):1996-2002.|[2]Schroder PM, et al. Preoperative carfilzomib and lulizumab based desensitization prolongs graft survival in a sensitized non-human primate model. Kidney Int. 2021 Jan;99(1):161-172.
- Research Area:
- Inflammation/Immunology
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Store at -80[o]C for 2 years
- Type:
- Antibodies
- Pathway:
- Immunology/Inflammation
