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Antibodies

Lokivetmab

Product Sizes
1 mg
£ POA
HY-P99301-1MG
10 mg
£ POA
HY-P99301-10MG
5 mg
£ POA
HY-P99301-5MG
About this Product
SKU:
HY-P99301
Additional Names:
Anti-Canine IL31 Recombinant Antibody; CAN34D3-65; PF-06443537
CAS Number:
1533403-95-0
Extra Details:
Lokivetmab (Anti-Canine IL31 Recombinant Antibody) is an anti-canine IL-31 monoclonal antibody. Lokivetmab inhibits IL-31-mediated activation of pruritogenic signals in peripheral sensory neurons and reduces TH2-weighted inflammation. Lokivetmab demonstrates long-term efficacy in controlling pruritus and improving skin lesions in dogs with canine atopic dermatitis (CAD). Lokivetmab can be used for the research of atopic dermatitis (AD) in dogs[1].
Molecular Weight:
(147.51 kDa)
Purity:
99.0
References:
[1]Meichner K, et al. Lokivetmab therapy for pruritus in a dog with cutaneous mastocytosis. Vet Dermatol. 2019 Feb;30(1):73-e22.
Research Area:
Inflammation/Immunology
Shipping Conditions:
Dry Ice
Storage Conditions:
Store at -80[o]C for 2 years
Type:
Antibodies
Pathway:
Immunology/Inflammation
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