Lampalizumab
Product Sizes
5 mg
HY-P99298-5MG
1 mg
HY-P99298-1MG
10 mg
HY-P99298-10MG
About this Product
- SKU:
- HY-P99298
- Additional Names:
- RG 7417; TNX 234; Anti-CFD Recombinant Antibody
- CAS Number:
- 1278466-20-8
- Extra Details:
- Lampalizumab (RG 7417) is a humanised monoclonal antibody targeting complement Factor D in the alternative complement pathway. Lampalizumab binds an exosite and sterically blocks Factor B access to the active site. Lampalizumab can be used for age-related macular degeneration (AMD) research[1][2].
- Molecular Weight:
- (143.8 kDa)
- Purity:
- 99.46
- References:
- [1]Yuan X, et al. Small-molecule factor D inhibitors selectively block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome. Haematologica. 2017 Mar;102(3):466-475.|[2]Hanus J, et al. Current therapeutic developments in atrophic age-related macular degeneration. Br J Ophthalmol. 2016 Jan;100(1):122-7.
- Research Area:
- Inflammation/Immunology
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Store at -80[o]C for 2 years
- Type:
- Antibodies
- Pathway:
- Immunology/Inflammation
