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Antibodies

Adecatumumab

Product Sizes
1 mg
£ POA
HY-P99278-1MG
10 mg
£ POA
HY-P99278-10MG
5 mg
£ POA
HY-P99278-5MG
About this Product
SKU:
HY-P99278
Additional Names:
MT 201; Anti-Human EPCAM Recombinant Antibody
Application:
Antibody Microarray
CAS Number:
503605-66-1
Extra Details:
Adecatumumab (Anti-Human EPCAM Recombinant Antibody; MT201) is a full human monoclonal antibody of the IgG1 isotype; targeting human EpCAM. Adecatumumab is expressed in almost all adenocarcinomas; and its activity is not dependent of K-Ras status[1][2].
Molecular Weight:
(147.52 kDa)
Purity:
99.54
References:
[1]Kurtz JE, et al. Adecatumumab: an anti-EpCAM monoclonal antibody, from the bench to the bedside. Expert Opin Biol Ther. 2010 Jun;10(6):951-8. |[2]Lutterbuese P, et al. Exchanging human Fcgamma1 with murine Fcgamma2a highly potentiates anti-tumor activity of anti-EpCAM antibody adecatumumab in a syngeneic mouse lung metastasis model. Cancer Immunol Immunother. 2007 Apr;56(4):459-68.
Research Area:
Cancer
Shipping Conditions:
Dry Ice
Storage Conditions:
Store at -80[o]C for 2 years
Type:
Antibodies
Pathway:
Others
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