Inotuzumab (powder)
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HY-P99264A-1EACH
About this Product
- SKU:
- HY-P99264A
- Additional Names:
- Humanized Anti-CD22 Recombinant Antibody (powder)
- Application:
- Antibody Microarray
- CAS Number:
- 1660159-36-3
- Extra Details:
- Inotuzumab (Humanized Anti-CD22 Recombinant Antibody) (powder) is a humanized IgG4κ antibody that targets human CD22. Inotuzumab (powder) can be linked to a toxic agent Ozogamicin as an antibody-drug conjugate (ADC); Inotuzumab ozogamicin (HY-P9959). Inotuzumab (powder) can be used for the research of acute lymphoblastic leukemia and non-Hodgkin lymphoma[1][2][3][4]. x
- Molecular Weight:
- (146.48 kDa)
- References:
- [1]Aujla A, et al. Inotuzumab ozogamicin in clinical development for acute lymphoblastic leukemia and non-Hodgkin lymphoma. Biomark Res. 2019 Apr 11;7:9.|[2]Wynne J, et al. Inotuzumab: from preclinical development to success in B-cell acute lymphoblastic leukemia. Blood Adv. 2019 Jan 8;3(1):96-104. |[3]Kirchhoff H, et al. Venetoclax and dexamethasone synergize with inotuzumab ozogamicin-induced DNA damage signaling in B-lineage ALL. Blood. 2021 May 13;137(19):2657-2661.|[4]Betts AM, et al. Preclinical to Clinical Translation of Antibody-Drug Conjugates Using PK/PD Modeling: a Retrospective Analysis of Inotuzumab Ozogamicin. AAPS J. 2016 Sep;18(5):1101-1116.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Antibodies
