Anti-H3L Antibody (NAL_A185)
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£ POA
HY-P992081-1EACH
Get quote
£ POA
HY-P992081-1EACH
About this Product
- SKU:
- HY-P992081
- Extra Details:
- Anti-H3L Antibody (NAL_A185) is a neutralizing antibody targeting the H3L envelope protein of vaccinia virus (CV) belonging to the genus Orthopoxvirus. By binding to the H3L protein of intracellular mature virions; Anti-H3L Antibody (NAL_A185) blocks the binding of the virus to host cells; thereby neutralizing viral infectivity. Anti-H3L Antibody (NAL_A185) not only protects BALB/c mice from intranasal challenge with the lethal vaccinia virus WR strain; reducing weight loss and mortality; but also exhibits complement-dependent neutralizing activity against monkeypox virus. Among these properties; NAL_A185 is an immune target induced by the smallpox vaccine Dryvax; it elicits a robust recall antibody response and induces high-titer neutralizing antibodies in mice. Anti-H3L Antibody (NAL_A185) can be used for studies related to vaccinia virus infection; monkeypox and monkeypox disease[1][2][3].
- Research Area:
- Infection
- Shipping Conditions:
- Ambient
- Type:
- Antibodies
