Anti-Mouse CD1d Antibody (1B1)
Product Sizes
Get quote
£ POA
HY-P992059-1EACH
About this Product
- SKU:
- HY-P992059
- Extra Details:
- Anti-Mouse CD1d Antibody (1B1) is an antibody targeting mouse CD1d (Kd = 12.5 nM). By inserting into the lipid-binding groove of CD1d; Anti-Mouse CD1d Antibody (1B1) overlaps with the binding sites of type I and type II NKT cell receptors (TCR); thereby effectively blocking TCR-mediated interactions. Anti-Mouse CD1d Antibody (1B1) activates antigen-presenting cells such as dendritic cells and macrophages; induces them to release IL-12p70; and increases the levels of key cytokines including IL-12; IFN-γ and IFN-α in mouse serum. Anti-Mouse CD1d Antibody (1B1) can be used in studies related to renal cancer; breast cancer and colon adenocarcinoma. When combined with anti-DR5 or anti-CD137 antibodies and chemotherapeutic drugs; Anti-Mouse CD1d Antibody (1B1) exhibits significant tumor inhibitory and even eradication effects in mice[1][2].
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Antibodies
