Durvalumab (anti-PD-L1)
Product Sizes
5 mg
£ POA
HY-P9919A-5MG
1 mg
£ POA
HY-P9919A-1MG
About this Product
- SKU:
- HY-P9919A
- Additional Names:
- MEDI 4736 (anti-PD-L1)
- CAS Number:
- 1428935-60-7
- Extra Details:
- Durvalumab (anti-PD-L1)(MEDI 4736) is a human anti-PD-L1 protein monoclonal antibody. Durvalumab (anti-PD-L1) completely blocks PD-L1 binding to PD-1 and CD80; IC 50 are 0.1 and 0.04 nM respectively; has anti-tumor activity[1][2].
- Molecular Weight:
- (146.32 kDa)
- Purity:
- 99.0
- References:
- [1]Faiena I, et al. Durvalumab: an investigational anti-PD-L1 monoclonal antibody for the treatment of urothelial carcinoma. Drug Des Devel Ther. 2018 Jan 23;12:209-215.|[2]Stewart R, et al. Identification and Characterization of MEDI4736, an Antagonistic Anti-PD-L1 Monoclonal Antibody. Cancer Immunol Res. 2015 Sep;3(9):1052-62.
- Research Area:
- Cancer
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Store at -80[o]C for 2 years
- Type:
- Antibodies
- Pathway:
- Immunology/Inflammation
