BSI-001
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HY-P991977-1EACH
About this Product
- SKU:
- HY-P991977
- Additional Names:
- 5G9
- Extra Details:
- BSI-001 (5G9) is a HER2-targeting antibody. BSI-001 inhibits cell proliferation and migration; induces apoptosis and PARP cleavage; and suppresses HER2-mediated downstream signaling pathways (including the phosphorylation of EGFR; HER3; AKT and ERK) when combined with Trastuzumab (HY-P9907) in HER2-positive cancer cells. BSI-001 exhibits synergistic anti-tumor efficacy in animal models of gastric cancer and breast cancer when combined with Trastuzumab. BSI-001 can be used for the research of HER2-positive breast cancer and HER2-overexpressing gastric cancer[1].
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Antibodies
