ART5803
Product Sizes
10 mg
HY-P991611-10MG
1 mg
HY-P991611-1MG
5 mg
HY-P991611-5MG
About this Product
- SKU:
- HY-P991611
- CAS Number:
- 3058434-76-4
- Extra Details:
- ART5803 is a humanized IgG1 monoclonal antibody inhibitor targeting NMDAR. ART5803 binds to the N-terminal domain (NTD) of the NMDAR GluN1 subunit (GluN1-NTD) with a high affinity. ART5803 blocks NMDAR internalization induced by pathogenic autoantibodies and restores cell-surface NMDAR expression and functions. ART5803 reverses behavioral abnormalities and NMDAR expression in marmoset disease models. ABT-147 can be used to study anti-NMDAR encephalitis[1].
- Molecular Weight:
- (146.05 kDa)
- Purity:
- 98.64
- Research Area:
- Inflammation/Immunology
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -80[o]C
- Type:
- Antibodies
