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Antibodies

ABX-MA1

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HY-P991609-1EACH
About this Product
SKU:
HY-P991609
CAS Number:
561063-60-3
Extra Details:
ABX-MA1 is a humanized IgG2 monoclonal antibody inhibitor targeting MCAM/MUC18. ABX-MA1 significantly decreases homotypic aggregation and heterotypic adhesion to HUVECs; and the formation of experimental lung metastasis. ABX-MA1 potently inhibits tumor growth; angiogenesis; and MMP-2 expression in A375SM/WM2664 xenograft mice model; promising for melanoma research[1].
References:
[1]Braeuer RR, et al. Transcriptional control of melanoma metastasis: the importance of the tumor microenvironment. Semin Cancer Biol. 2011 Apr;21(2):83-8.
Research Area:
Cancer
Shipping Conditions:
Ambient
Type:
Antibodies
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