Daratumumab (Anti-CD38)
Product Sizes
5 mg
£ POA
HY-P9915A-5MG
10 mg
£ POA
HY-P9915A-10MG
1 mg
£ POA
HY-P9915A-1MG
About this Product
- SKU:
- HY-P9915A
- Additional Names:
- Anti-Human CD38; Human Antibody (PBS)
- Application:
- Antibody Microarray
- CAS Number:
- 945721-28-8
- Extra Details:
- Daratumumab (PBS) (Anti-Human CD38) is the first-in-class human-specific anti-CD38 monoclonal antibody (IgG1). Daratumumab (PBS) has anti-multiple myeloma (MM) effect. Daratumumab (PBS) impairs MM cell adhesion; which results in an increased sensitivity of MM to proteasome inhibition[1][2].
- Molecular Weight:
- (145.26 kDa)
- Purity:
- 95.41
- References:
- [1]Ghose J, Viola D, et al. Daratumumab induces CD38 internalization and impairs myeloma cell adhesion. Oncoimmunology. 2018;7(10):e1486948. Published 2018 Jul 23.|[2]de Weers M, et al. Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors. J Immunol. 2011;186(3):1840-1848.
- Research Area:
- Cancer
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Store at -80[o]C for 2 years
- Type:
- Antibodies
- Pathway:
- Antibody-drug Conjugate/ADC Related;Immunology/Inflammation
