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Antibodies

Anti-CD20 Antibody (mAb 1.5.3)

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HY-P991547-1EACH
About this Product
SKU:
HY-P991547
CAS Number:
922534-56-3
Extra Details:
Anti-CD20 Antibody (mAb 1.5.3) is a fully human IgG1 anti-CD20 antibody. Anti-CD20 Antibody (mAb 1.5.3) evokes enhanced pro-apoptotic activity in vitro. Anti-CD20 Antibody (mAb 1.5.3) mediated both complement-dependent cytotoxicity and antibody-dependent cellular cytotoxicity. Anti-CD20 Antibody (mAb 1.5.3) demonstrates enhanced anti-tumor activity in various tumor xenograft models. Anti-CD20 Antibody (mAb 1.5.3) produces a superior B-cell depletion profile in lymph node organs and bone marrow in a primate pharmacodynamic model. Anti-CD20 Antibody (mAb 1.5.3) can be studied in research for B-cell maglignancies[1].
References:
[1]Bornstein, G. G., et al., (2010). Development of a new fully human anti-CD20 monoclonal antibody for the treatment of B-cell malignancies. Investigational new drugs, 28(5), 561–574.
Research Area:
Cancer; Inflammation/Immunology
Shipping Conditions:
Ambient
Type:
Antibodies
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