AGEN-2373
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HY-P991529-1EACH
About this Product
- SKU:
- HY-P991529
- Extra Details:
- AGEN-2373 is a conditionally active agonist antibody targeting the co-stimulatory receptor CD137. GEN-2373 binds to CD137 without disruption of ligand binding. AGEN-2373 stimulates CD137 under receptor clustering conditions. AGEN-2373 can enhance T cell activity when combined with other checkpoint modulators (e.g. PD-1 antagonist and OX40 agonist). AGEN-2373 can be studied in research for human malignancies[1].
- References:
- [1]Claire Galand, et al., AGEN2373 is a conditionally-active agonist antibody targeting the co-stimulatory receptor CD137 for the treatment of human malignancies. Journal of Clinical Oncology, 2019.
- Research Area:
- Cancer; Inflammation/Immunology
- Shipping Conditions:
- Ambient
- Type:
- Antibodies
